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Michael J Detke Selected Research

Major Depressive Disorder (Major Depressive Disorders)

3/2011Sexual function during long-term duloxetine treatment in patients with recurrent major depressive disorder.
11/2010Long-term safety of duloxetine during open-label compassionate use treatment of patients who completed previous duloxetine clinical trials.
5/2009Duloxetine in the prevention of depressive recurrences: a randomized, double-blind, placebo-controlled trial.
11/2008The relationship between antidepressant and analgesic responses: findings from six placebo-controlled trials assessing the efficacy of duloxetine in patients with major depressive disorder.
9/2008A randomized, double-blind study of increasing or maintaining duloxetine dose in patients without remission of major depressive disorder after initial duloxetine therapy.
6/2008Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial.
5/2008Clinical evidence for serotonin and norepinephrine reuptake inhibition of duloxetine.
12/2007Efficacy of duloxetine and selective serotonin reuptake inhibitors: comparisons as assessed by remission rates in patients with major depressive disorder.
11/2007Evidence for the efficacy of duloxetine in treating mild, moderate, and severe depression.
8/2007Duloxetine in the treatment of major depressive disorder: an open-label study.
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Michael J Detke Research Topics

Disease

27Major Depressive Disorder (Major Depressive Disorders)
03/2011 - 01/2002
13Pain (Aches)
06/2010 - 11/2002
6Neuralgia (Stump Neuralgia)
11/2010 - 07/2005
6Fibromyalgia (Fibrositis)
11/2010 - 09/2004
6Nausea
06/2010 - 11/2002
5Anxiety Disorders (Anxiety Disorder)
11/2010 - 01/2007
4Dizziness (Lightheadedness)
06/2010 - 11/2002
4Sleep Initiation and Maintenance Disorders (Insomnia)
08/2007 - 08/2004
4Back Pain (Backache)
03/2005 - 11/2002
3Constipation
06/2010 - 11/2002
3Sleepiness
01/2008 - 12/2004
3Medically Unexplained Symptoms
11/2007 - 01/2004
3Shoulder Pain
01/2005 - 11/2002
2Weight Gain
06/2014 - 01/2006
2Fatigue
06/2010 - 11/2008
2Diarrhea
06/2010 - 12/2004
2Headache (Headaches)
08/2007 - 12/2004
1Alcoholism (Alcohol Abuse)
01/2016
1Schizophrenia (Dementia Praecox)
06/2014
1Chronic Pain
06/2010
1Hyperhidrosis
06/2010
1Osteoarthritis
06/2010
1Low Back Pain (Lumbago)
06/2010
1Mental Fatigue
11/2008
1Hypochondriasis
01/2007
1Body Weight (Weight, Body)
01/2006
1Mania (Manias)
07/2005
1Polyneuropathies (Polyneuropathy)
07/2005
1Diabetic Neuropathies (Diabetic Neuropathy)
07/2005
1Type 2 Diabetes Mellitus (MODY)
07/2005
1Bipolar Disorder (Manic Depressive Psychosis)
07/2005
1Weight Loss (Weight Reduction)
01/2005
1Virus Diseases (Viral Diseases)
12/2004
1Mood Disorders (Mood Disorder)
06/2002
1Cocaine-Related Disorders (Cocaine Addiction)
06/2002

Drug/Important Bio-Agent (IBA)

37Duloxetine Hydrochloride (Cymbalta)FDA Link
03/2011 - 01/2002
8Norepinephrine (Noradrenaline)FDA LinkGeneric
06/2010 - 01/2004
8Serotonin (5 Hydroxytryptamine)IBA
06/2010 - 01/2004
5Paroxetine (Paxil)FDA LinkGeneric
12/2007 - 08/2004
3Antidepressive Agents (Antidepressants)IBA
03/2011 - 07/2005
2Pharmaceutical PreparationsIBA
05/2008 - 06/2006
2Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
12/2007 - 01/2007
1Indicators and Reagents (Reagents)IBA
01/2016
1vabicaserinIBA
06/2014
1Olanzapine (Zyprexa)FDA Link
06/2014
1Analgesics (Analgesic Drugs)IBA
11/2008
1Serotonin and Noradrenaline Reuptake InhibitorsIBA
12/2007
1Fluoxetine (Prozac)FDA LinkGeneric
12/2007
1Phospholipids (Phosphatides)FDA LinkGeneric
06/2002

Therapy/Procedure

5Therapeutics
11/2010 - 11/2002